Professional and Linguistic Assessments Board (PLAB) Practice Exam

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Which drug is commonly used to treat hypothyroidism?

Hydrocodone
Levothyroxine
Clonazepam
Fludrocortisone

The correct answer is: Levothyroxine

Levothyroxine is the standard medication used to treat hypothyroidism by providing the body with the synthetic form of the thyroid hormone thyroxine (T4). In hypothyroidism, the thyroid gland does not produce enough hormones, leading to symptoms like fatigue, weight gain, and depression. Levothyroxine helps to normalize hormone levels, alleviating these symptoms and restoring metabolic function. Other medications listed are not used for hypothyroidism. Hydrocodone is an opioid pain medication, clonazepam is primarily used for anxiety and seizure disorders, and fludrocortisone is a corticosteroid used to treat conditions where there is insufficient mineralocorticoid hormone production, such as Addison's disease. None of these address the deficiency of thyroid hormones that characterize hypothyroidism, making levothyroxine the correct answer.